Unii metaboliți de steroli pot imita hormonii tipici din organism și pot concura cu aceștia pentru receptorii din celulele corpului. It seems that only the free amount of testosterone can bind to an androgenic receptor, which means they have biological activity. A recent study, for example, suggests that TRT provides extra benefit for overall mortality and stroke for men whose testosterone levels have normalized with TRT. In general, androgens such as testosterone promote protein synthesis and thus growth of tissues with androgen receptors.

The 6β-hydroxylation of testosterone is catalyzed mainly by CYP3A4 and to a lesser extent CYP3A5 and is responsible for 75 to 80% of cytochrome P450-mediated testosterone metabolism. Indiferent de sex, cresterea testosteronului este semnificativa la pubertate si incepe sa scada dupa varsta de 30 ani.The increases were higher in the athletes, which suggests that magnesium boost testosterone in men with normal levels. In people who have undergone testosterone deprivation therapy, testosterone increases beyond the castrate level have been shown to increase the rate of spread of an existing prostate cancer. Finally, increasing levels of testosterone through a negative feedback loop act on the hypothalamus and pituitary to inhibit the release of GnRH and FSH/LH, respectively. Desi, in cazul barbatilor mai ales, testosteronul seric este important din punct de vedere al calitatii vietii, terapia de substitutie hormonala nu este inca suficient studiata incat sa fie recomandata in mod curent.

Taking something that you don't need could potentially cause irreversible issues – so for that reason, steroid hormones like DHEA should never be prescribed without blood tests. As the metabolism of testosterone in males is more pronounced, the daily production is about 20 times greater in men. Common side effects from testosterone medication include acne, swelling, and breast enlargement in males. A validated age-related normative model for male total testosterone shows increasing variance but no decline after age 40 years". Extra virgin olive oil – A 2013 study found that men were able to boost their testosterone levels by consuming extra virgin olive oil over the course of three weeks.

This could explain why some studies find a link between testosterone and pro-social behaviour if pro-social behaviour is rewarded with social status.